Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations.
Lingor P, Koch JC, Statland JM, Hussain S, Hennecke C, Wuu J, Langbein T, Ahmed R, Günther R, Ilse B, Kassubek J, Kollewe K, Kuttler J, Leha A, Lengenfeld T, Meyer T, Neuwirth C, Tostmann R, Benatar M.
Amyotroph Lateral Scler Frontotemporal Degener. 2021 Feb 3:1-7. doi: 10.1080/21678421.2021.1879866. Online ahead of print.
[PubMed]

Case Report: Association of a Variant of Unknown Significance in the FIG4 Gene With Frontotemporal Dementia and Slowly Progressing Motoneuron Disease: A Case Report Depicting Common Challenges in Clinical and Genetic Diagnostics of Rare Neuropsychiatric and Neurologic Disorders.
Bergner CG, Neuhofer CM, Funke C, Biskup S, von Gottberg P, Bartels C, Koch JC, Radenbach K.
Front Neurosci. 2020 Dec 22;14:559670. doi: 10.3389/fnins.2020.559670. eCollection 2020.
[PubMed]

Rho-kinase inhibition by fasudil modulates pre-synaptic vesicle dynamics.
Saal KA, Warth Pérez Arias C, Roser AE, Christoph Koch J, Bähr M, Rizzoli SO, Lingor P.
J Neurochem. 2020 Dec 20. doi: 10.1111/jnc.15274. Online ahead of print.
[PubMed]

TDP-43 as structure-based biomarker in amyotrophic lateral sclerosis.
Beyer L, Günther R, Koch JC, Klebe S, Hagenacker T, Lingor P, Biesalski AS, Hermann A, Nabers A, Gold R, Tönges L, Gerwert K.
Ann Clin Transl Neurol. 2021 Jan;8(1):271-277. doi: 10.1002/acn3.51256. Epub 2020 Dec 2.
[PubMed]

Genetic prion disease: opportunities for early therapeutic intervention with rigorous pre-symptomatic trials.
Hermann P, Koch JC, Zerr I.
Expert Opin Investig Drugs. 2020 Dec;29(12):1313-1316. doi: 10.1080/13543784.2020.1839048. Epub 2020 Nov 1.
[PubMed]

Neue Therapieansätze bei der amyotrophen Lateralsklerose
Arzneimitteltherapie. 2020 October; 38:274-83.
Cordts I, Koch JC, Lingor P.
Arzneimitteltherapie. 2020 October; 38:274-83.

Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities.
Steel D, Zech M, Zhao C, Barwick KES, Burke D, Demailly D, Kumar KR, Zorzi G, Nardocci N, Kaiyrzhanov R, Wagner M, Iuso A, Berutti R, Škorvánek M, Necpál J, Davis R, Wiethoff S, Mankad K, Sudhakar S, Ferrini A, Sharma S, Kamsteeg EJ, Tijssen MA, Verschuuren C, van Egmond ME, Flowers JM, McEntagart M, Tucci A, Coubes P, Bustos BI, Gonzalez-Latapi P, Tisch S, Darveniza P, Gorman KM, Peall KJ, Bötzel K, Koch JC, Kmieć T, Plecko B, Boesch S, Haslinger B, Jech R, Garavaglia B, Wood N, Houlden H, Gissen P, Lubbe SJ, Sue CM, Cif L, Mencacci NE, Anderson G, Kurian MA, Winkelmann J;
Genomics England Research Consortium. Ann Neurol. 2020 Nov;88(5):867-877. doi: 10.1002/ana.25879. Epub 2020 Sep 21.
[PubMed]

Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing.
Vahsen BF, Ribas VT, Sundermeyer J, Boecker A, Dambeck V, Lenz C, Shomroni O, Caldi Gomes L, Tatenhorst L, Barski E, Roser AE, Michel U, Urlaub H, Salinas G, Bähr M, Koch JC, Lingor P.
Cell Death Differ. 2020 Apr 27;.doi: 10.1038/s41418-020-0543-y. [Epub ahead of print] PubMed PMID: 32341448.
[PubMed]

Demyelinating neuropathy and local toxicity caused by extravasated Brentuximab vedotin.
Hoffmann JC, Soliman M, Koch JC, Liman J, Schön MP, Mitteldorf C.
J Eur Acad Dermatol Venereol.2020 Apr 20;. doi: 10.1111/jdv.16502. [Epub ahead of print] PubMed PMID: 32311792.
[PubMed]

Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study.
Hagenacker T, Wurster CD, Günther R, Schreiber-Katz O, Osmanovic A, Petri S, Weiler M, Ziegler A, Kuttler J, Koch JC, Schneider I, Wunderlich G, Schloss N, Lehmann HC, Cordts I, Deschauer M, Lingor P, Kamm C, Stolte B, Pietruck L, Totzeck A, Kizina K, Mönninghoff C, von Velsen O, Ose C, Reichmann H, Forsting M, Pechmann A, Kirschner J, Ludolph AC, Hermann A, Kleinschnitz C.
Lancet Neurol.2020 Apr;19(4):317-325. doi: 10.1016/S1474-4422(20)30037-5.Epub 2020 Mar 18. PubMed PMID: 32199097
[PubMed]

Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis.
Koch JC, Kuttler J, Maass F, Lengenfeld T, Zielke E, Bähr M, Lingor P.
Front Neurol. 2020;11:173doi: 10.3389/fneur.2020.00173.eCollection 2020.PubMed PMID: 32231638; PubMed Central PMCID: PMC7083210.
[PubMed]

SQSTM1/p62 variants in 486 patients with familial ALS from Germany and Sweden.
Yilmaz R, Müller K, Brenner D, Volk AE, Borck G, Hermann A, Meitinger T, Strom TM, Danzer KM, Ludolph AC, Andersen PM, Weishaupt JH.
Neurobiol Aging. 2020 Mar;87:139.e9-139.e15. doi: 10.1016/j.neurobiolaging.2019.10.018. Epub 2019 Nov 2. class=“pmid“>PubMed PMID:31859009.

Therapiemöglichkeiten bei fortgeschrittener Amyotropher Lateralsklerose.
Lengenfeld T, Koch JC.
Internistische Praxis. 2020; 61<:646-660.

Routine Cerebrospinal Fluid (CSF) Parameters in Patients With Spinal Muscular Atrophy (SMA) Treated With Nusinersen.
Wurster CD, Koch JC, Cordts I, Dreyhaupt J, Otto M, Uzelac Z, Witzel S, Winter B, Kocak T, Schocke M, Weydt P, Wollinsky K, Ludolph AC, Deschauer M, Lingor P, Tumani H, Hermann A, Günther R.
Front Neurol.2019;10:1179. doi: 10.3389/fneur.2019.01179. eCollection 2019. PubMed PMID: 31787927; PubMed Central PMCID: PMC6854024.
[PubMed]

Patient-Reported Prevalence of Non-motor Symptoms Is Low in Adult Patients Suffering From 5q Spinal Muscular Atrophy.
Günther R, Wurster CD, Cordts I, Koch JC, Kamm C, Petzold D, Aust E, Deschauer M, Lingor P, Ludolph AC, Hermann A.
Front Neurol. 2019;10:1098doi: 10.3389/fneur.2019.01098. eCollection 2019.PubMed PMID: 31736847; PubMed Central PMCID: PMC6838202.
[PubMed]

Prognostic factors in ALS: a comparison between Germany and China.
Dorst J, Chen L, Rosenbohm A, Dreyhaupt J, Hübers A, Schuster J, Weishaupt JH, Kassubek J, Gess B, Meyer T, Weyen U, Hermann A, Winkler J, Grehl T, Hagenacker T, Lingor P, Koch JC, Sperfeld A, Petri S, Großkreutz J, Metelmann M, Wolf J, Winkler AS, Klopstock T, Boentert M, Johannesen S, Storch A, Schrank B, Zeller D, Liu XL, Tang L, Fan DS, Ludolph AC.
J Neurol. 2019 Jun;266(6):1516-1525.doi: 10.1007/s00415-019-09290-4.Epub 2019 Mar 28.
[PubMed]

Neurochemical markers in CSF of adolescent and adult SMA patients undergoing nusinersen treatment.
Wurster CD, Günther R, Steinacker P, Dreyhaupt J, Wollinsky K, Uzelac Z, Witzel S, Kocak T, Winter B, Koch JC, Lingor P, Petri S, Ludolph AC, Hermann A, Otto M.
Ther Adv Neurol Disord. 2019 May 10;12:1756286419846058. doi: 10.1177/1756286419846058. eCollection 2019.
[PubMed]

Neurofilament light chain in serum of adolescent and adult SMA patients under treatment with nusinersen.
Wurster CD, Steinacker P, Günther R, Koch JC, Lingor P, Uzelac Z, Witzel S, Wollinsky K, Winter B, Osmanovic A, Schreiber-Katz O, Al Shweiki R, Ludolph AC, Petri S, Hermann A, Otto M; MND-Net.
J Neurol. 2019 Sep 24. doi: 10.1007/s00415-019-09547-y. [Epub ahead of print] [PubMed]

ROCK-ALS: Protocol for a Randomized, Placebo-Controlled, Double-Blind Phase IIa Trial of Safety, Tolerability and Efficacy of the Rho Kinase (ROCK) Inhibitor Fasudil in Amyotrophic Lateral Sclerosis.
Lingor P, Weber M, Camu W, Friede T, Hilgers R, Leha A, Neuwirth C, Günther R, Benatar M, Kuzma-Kozakiewicz M, Bidner H, Blankenstein C, Frontini R, Ludolph A, Koch JC; ROCK-ALS Investigators.
Front Neurol. 2019 Mar 27;10:293. doi: 10.3389/fneur.2019.00293. eCollection 2019.
[PubMed]

Prognostic factors in ALS: a comparison between Germany and China.
Dorst J, Chen L, Rosenbohm A, Dreyhaupt J, Hübers A, Schuster J, Weishaupt JH, Kassubek J, Gess B, Meyer T, Weyen U, Hermann A, Winkler J, Grehl T, Hagenacker T, Lingor P, Koch JC, Sperfeld A, Petri S, Großkreutz J, Metelmann M, Wolf J, Winkler AS, Klopstock T, Boentert M, Johannesen S, Storch A, Schrank B, Zeller D, Liu XL, Tang L, Fan DS, Ludolph AC.
J Neurol. 2019 Jun;266(6):1516-1525. doi: 10.1007/s00415-019-09290-4. Epub 2019 Mar 28.
[PubMed]

Quantification of spinal cord compression using T1 mapping in patients with cervical spinal canal stenosis – Preliminary experience.
Maier IL, Hofer S, Joseph AA, Merboldt KD, Eggert E, Behme D, Schregel K, von der Brelie C, Rohde V, Koch J, Psychogios MN, Frahm J, Liman J, Bähr M.
Neuroimage Clin. 2019;21:101639. doi: 10.1016/j.nicl.2018.101639. Epub 2018 Dec 10.
[PubMed]

Motor Unit Number Index (MUNIX) of hand muscles is a disease biomarker for adult spinal muscular atrophy.
Günther R, Neuwirth C, Koch JC, Lingor P, Braun N, Untucht R, Petzold D, Weber M, Hermann A.
Clin Neurophysiol. 2018 Nov 24. pii: S1388-2457(18)31356-7. doi: 10.1016/j.clinph.2018.11.009.
[PubMed]

ROCK inhibition in models of neurodegeneration and its potential for clinical translation.
Tatenhorst L, Roser AE, Saal KA, Tönges L, Lingor P.
Pharmacol Ther. 2018 Sep;189:1-21. doi: 10.1016/j.pharmthera.2018.03.008. Epub 2018 Apr 3.
[PubMed]

Comprehensive analysis of the mutation spectrum in 301 German ALS families.
Müller K, Brenner D, Weydt P, Meyer T, Grehl T, Petri S, Grosskreutz J, Schuster J, Volk AE, Borck G, Kubisch C, Klopstock T, Zeller D, Jablonka S, Sendtner M, Klebe S, Knehr A, Günther K, Weis J, Claeys KG, Schrank B, Sperfeld AD, Hübers A, Otto M, Dorst J, Meitinger T, Strom TM, Andersen PM, Ludolph AC, Weishaupt JH; German ALS network MND-NET.
J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):817-827. doi: 10.1136/jnnp-2017-317611. Epub 2018 Apr 12.
[PubMed]

Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson’s disease.
Maass F, Michalke B, Leha A, Boerger M, Zerr I, Koch JC, Tönges L, Bähr M, Lingor P.
J Neurochem. 2018 May;145(4):342-351. doi: 10.1111/jnc.14316. Epub 2018 Apr 2.
[PubMed]

MDS1 and EVI1 complex locus MECOM: a novel candidate gene for hereditary hematological malignancies.
Ripperger T, Hofmann W, Koch JC, Shirneshan K, Haase D, Wulf G, Issing PR, Karnebogen M, Schmidt G, Auber B, Schlegelberger B, Illig T, Zirn B, Steinemann D.
Haematologica. 2018 Feb;103(2):e55-e58. doi: 10.3324/haematol.2017.178723. Epub 2017 Nov 2. No abstract available.
[PubMed]

Hot-spot KIF5A mutations cause familial ALS.
Brenner D, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, Jordan B, Knehr A, Günther K, Hübers A, Zeller D, Kubisch C, Jablonka S, Sendtner M, Klopstock T, de Carvalho M, Sperfeld A, Borck G, Volk AE, Dorst J, Weis J, Otto M, Schuster J, Del Tredici K, Braak H, Danzer KM, Freischmidt A, Meitinger T, Strom TM, Ludolph AC, Andersen PM, Weishaupt JH; German ALS network MND-NET .
Brain. 2018 Mar 1;141(3):688-697. doi: 10.1093/brain/awx370.
[PubMed]

ENCALS statement on edaravone.
Al-Chalabi A, Andersen PM, Chandran S, Chio A, Corcia P, Couratier P, Danielsson O, de Carvalho M, Desnuelle C, Grehl T, Grosskreutz J, Holmøy T, Ingre C, Karlsborg M, Kleveland G, Koch JC, Koritnik B, KuzmaKozakiewicz M, Laaksovirta H, Ludolph A, McDermott C, Meyer T, Mitre Ropero B, Mora Pardina J, Nygren I, Petri S, Povedano Panades M, Salachas F, Shaw P, Silani V, Staaf G, Svenstrup K, Talbot K, Tysnes OB, Van Damme P, van der Kooi A, Weber M, Weydt P, Wolf J, Hardiman O, van den Berg LH.
Amyotroph Lateral Scler Frontotemporal Degener. 2017 Nov;18(7-8):471-474. doi: 10.1080/21678421.2017.1369125. Epub 2017 Oct 4. Review. No abstract available.
[PubMed]

Collapsin response mediator protein-2 plays a major protective role in acute axonal degeneration.
Zhang JN, Koch JC.
Neural Regen Res. 2017 May;12(5):692-695. doi: 10.4103/1673-5374.206631. Review.
[PubMed]

Alpha-synuclein and iron: two keys unlocking Parkinson’s disease.
Lingor P, Carboni E, Koch JC.
J Neural Transm (Vienna). 2017 Aug;124(8):973-981. doi: 10.1007/s00702-017-1695-x. Epub 2017 Feb 6. Review.
[PubMed]

Rho Kinase Inhibition with Fasudil in the SOD1^G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset.
Günther R, Balck A, Koch JC, Nientiedt T, Sereda M, Bähr M, Lingor P, Tönges L.
Front Pharmacol. 2017 Jan 31;8:17. doi: 10.3389/fphar.2017.00017. eCollection 2017.
[PubMed]

Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.
Ribas VT, Koch JC, Michel U, Bähr M, Lingor P.
Mol Neurobiol. 2017 Jan;54(1):72-86. doi: 10.1007/s12035-015-9676-2. Epub 2016 Jan 5.
[PubMed]

Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration.
Zhang JN, Michel U, Lenz C, Friedel CC, Köster S, d’Hedouville Z, Tönges L, Urlaub H, Bähr M, Lingor P, Koch JC.
Sci Rep. 2016 Nov 15;6:37050. doi: 10.1038/srep37050.
[PubMed]

The role of autophagy in axonal degeneration of the optic nerve.
Koch JC, Lingor P.
Exp Eye Res. 2016 Mar;144:81-9. doi: 10.1016/j.exer.2015.08.016. Epub 2015 Aug 24.
[PubMed]

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease.
Tatenhorst L, Eckermann K, Dambeck V, Fonseca-Ornelas L, Walle H, Lopes da Fonseca T, Koch JC, Becker S, Tönges L, Bähr M, Outeiro TF, Zweckstetter M, Lingor P.
Acta Neuropathol Commun. 2016 Apr 22;4:39. doi: 10.1186/s40478-016-0310-y.
[PubMed]

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, (..), Koch JC, et al
Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. No abstract available. Erratum in: Autophagy. 2016;12(2):443. Selliez, Iban [corrected to Seiliez, Iban].
[PubMed]

Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.
Koch JC, Bitow F, Haack J, d’Hedouville Z, Zhang JN, Tönges L, Michel U, Oliveira LM, Jovin TM, Liman J, Tatenhorst L, Bähr M, Lingor P.
Cell Death Dis. 2015 Jul 9;6:e1811. doi: 10.1038/cddis.2015.169.
[PubMed]

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson’s disease in vitro and in vivo.
Saal KA, Koch JC, Tatenhorst L, Szegő EM, Ribas VT, Michel U, Bähr M, Tönges L, Lingor P.
Neurobiol Dis. 2015 Jan;73:150-62. doi: 10.1016/j.nbd.2014.09.013. Epub 2014 Oct 2.
[PubMed]

Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson’s patient-derived induced pluripotent stem cells.
Oliveira LM, Falomir-Lockhart LJ, Botelho MG, Lin KH, Wales P, Koch JC, Gerhardt E, Taschenberger H, Outeiro TF, Lingor P, Schüle B, Arndt-Jovin DJ, Jovin TM.
Cell Death Dis. 2015 Nov 26;6:e1994. doi: 10.1038/cddis.2015.318.
[PubMed]

AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.
Challagundla M, Koch JC, Ribas VT, Michel U, Kügler S, Ostendorf T, Bradke F, Müller HW, Bähr M, Lingor P.
J Neurochem. 2015 Jul;134(2):261-75. doi: 10.1111/jnc.13102. Epub 2015 Apr 13.
[PubMed]

Early and sustained activation of autophagy in degenerating axons after spinal cord injury.
Ribas VT, Schnepf B, Challagundla M, Koch JC, Bähr M, Lingor P.
Brain Pathol. 2015 Mar;25(2):157-70. doi: 10.1111/bpa.12170. Epub 2014 Sep 12.
[PubMed]

The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice.
Günther R, Saal KA, Suhr M, Scheer D, Koch JC, Bähr M, Lingor P, Tönges L.
Front Neurosci. 2014 Oct 7;8:304. doi: 10.3389/fnins.2014.00304. eCollection 2014.
[PubMed]

Alpha-synuclein mutations impair axonal regeneration in models of Parkinson’s disease.
Tönges L, Szegö EM, Hause P, Saal KA, Tatenhorst L, Koch JC, D Hedouville Z, Dambeck V, Kügler S, Dohm CP, Bähr M, Lingor P.
Front Aging Neurosci. 2014 Sep 10;6:239. doi: 10.3389/fnagi.2014.00239. eCollection 2014.
[PubMed]

Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells.
Koch JC, Tönges L, Michel U, Bähr M, Lingor P.
Front Cell Neurosci. 2014 Sep 5;8:273. doi: 10.3389/fncel.2014.00273. eCollection 2014.
[PubMed]

Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.
Tatenhorst L, Tönges L, Saal KA, Koch JC, Szegő ÉM, Bähr M, Lingor P.
J Neuropathol Exp Neurol. 2014 Aug;73(8):770-9. doi: 10.1097/NEN.0000000000000095.
[PubMed]

ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.
Koch JC, Tönges L, Barski E, Michel U, Bähr M, Lingor P.
Cell Death Dis. 2014 May 15;5:e1225. doi: 10.1038/cddis.2014.191.
[PubMed]

Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.
Tönges L, Günther R, Suhr M, Jansen J, Balck A, Saal KA, Barski E, Nientied T, Götz AA, Koch JC, Mueller BK, Weishaupt JH, Sereda MW, Hanisch UK, Bähr M, Lingor P.
Glia. 2014 Feb;62(2):217-32. doi: 10.1002/glia.22601. Epub 2013 Dec 6.
[PubMed]

MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation.
Doeppner TR, Doehring M, Bretschneider E, Zechariah A, Kaltwasser B, Müller B, Koch JC, Bähr M, Hermann DM, Michel U.
Acta Neuropathol. 2013 Aug;126(2):251-65. doi: 10.1007/s00401-013-1142-5. Epub 2013 Jun 11.
[PubMed]

Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro.
Koch JC, Solis GP, Bodrikov V, Michel U, Haralampieva D, Shypitsyna A, Tönges L, Bähr M, Lingor P, Stuermer CA.
Neurobiol Dis. 2013 Mar;51:168-76. doi: 10.1016/j.nbd.2012.11.007. Epub 2012 Nov 19
[PubMed]

X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons.
Dučić T, Barski E, Salome M, Koch JC, Bähr M, Lingor P.
J Neurochem. 2013 Jan;124(2):250-61. doi: 10.1111/jnc.12073. Epub 2012 Dec 5.
[PubMed]

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease.
Tönges L, Frank T, Tatenhorst L, Saal KA, Koch JC, Szego ÉM, Bähr M, Weishaupt JH, Lingor P.
Brain. 2012 Nov;135(Pt 11):3355-70. doi: 10.1093/brain/aws254. Epub 2012 Oct 19.
[PubMed]

Axonal degeneration as a therapeutic target in the CNS.
Lingor P, Koch JC, Tönges L, Bähr M.
Cell Tissue Res. 2012 Jul;349(1):289-311. doi: 10.1007/s00441-012-1362-3. Epub 2012 Mar 6.
[PubMed]

Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS).
Günther R, Suhr M, Koch JC, Bähr M, Lingor P, Tönges L.
J Vis Exp. 2012 Mar 17;(61). pii: 3936. doi: 10.3791/3936.
[PubMed]

Targeting Neurological Disease with siRNA. In: Controlled Genetic Manipulations.
Koch JC, Bähr M, Lingor P.
Morozov A, editor. New Jersey: Humana Press; 2012. 97-111p.

ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
Tönges L, Koch JC, Bähr M, Lingor P.
Front Mol Neurosci. 2011 Nov 3;4:39. doi: 10.3389/fnmol.2011.00039. eCollection 2011.
[PubMed]

Imaging of rat optic nerve axons in vivo.
Koch JC, Knöferle J, Tönges L, Michel U, Bähr M, Lingor P.
Nat Protoc. 2011 Nov 3;6(12):1887-96. doi: 10.1038/nprot.2011.403.
[PubMed]

Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression.
Koch JC, Barski E, Lingor P, Bähr M, Michel U.
FEBS J. 2011 Sep;278(18):3472-83. doi: 10.1111/j.1742-4658.2011.08269.x.
[PubMed]

JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.
Tönges L, Planchamp V, Koch JC, Herdegen T, Bähr M, Lingor P.
J Mol Neurosci. 2011 Oct;45(2):284-93. doi: 10.1007/s12031-011-9519-1. Epub 2011 Apr 6.
[PubMed]

Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo.
Tönges L, Ostendorf T, Lamballe F, Genestine M, Dono R, Koch JC, Bähr M, Maina F, Lingor P.
J Neurochem. 2011 Jun;117(5):892-903. doi: 10.1111/j.1471-4159.2011.07257.x. Epub 2011 Apr 26.
[PubMed]

Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner.
Koch JC, Knöferle J, Tönges L, Ostendorf T, Bähr M, Lingor P.
Autophagy. 2010 Jul;6(5):658-9. doi: 10.4161/auto.6.5.12188. Epub 2010 Jul 1.
[PubMed]

TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP.
Knöferle J, Ramljak S, Koch JC, Tönges L, Asif AR, Michel U, Wouters FS, Heermann S, Krieglstein K, Zerr I, Bähr M, Lingor P.
Neurobiol Dis. 2010 Jun;38(3):395-404. doi: 10.1016/j.nbd.2010.02.011. Epub 2010 Mar 6.
[PubMed]

Mechanisms of acute axonal degeneration in the optic nerve in vivo.
Knöferle J, Koch JC, Ostendorf T, Michel U, Planchamp V, Vutova P, Tönges L, Stadelmann C, Brück W, Bähr M, Lingor P.
Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6064-9. doi: 10.1073/pnas.0909794107. Epub 2010 Mar 15.
[PubMed]