• 2006 – 2014: Residency in Neurology, University Medicine Göttingen
  Departments of Neurology (Prof. M. Bähr) and Psychiatry (Prof. B. Bandelow)
  Specialist for Neurology 03/2014 (Medical Board Examination, Hannover, Germany)
• 1998 – 2006: Medical School, University of Freiburg, Germany
  License to practice medicine (Staatsexamen & Approbation) 05/2006
• 2002 – 2009: MD thesis (Dr. med.) in the Department of Neuroanatomy (Prof. M. Frotscher), University of Freiburg, Germany: “Structural and functional characteristics of neuronal networks during early postnatal development of the reeler mouse neocortex.”
  
• 2002 – 2003: Study of Chinese language and Chinese Medicine, University of Nanjing, China
• 1984 – 1997: Primary and High School, Wiehl, Germany,
  Exchange student at Washburn High School in Minneapolis, Minnesota, USA 1994-1995

• 2016 – present: Consultant for Neurology, Dept. of Neurology, University Medicine Göttingen
• 2017 – present: Independet research group leader, Dept. of Neurology, University Medicine Göttingen
• 2015 – 2018: Principal Investigator, DFG-Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen
• 2006 – 2014: Postdoctoral fellow, Lingor Lab, Dept. of Neurology, University Medicine Göttingen
• 2012 – 2013: Resident in Psychiatry, Dept. of Psychiatry, University Medicine Göttingen
• 2006 -2012: Resident in Neurology, Dept. of Neurology, University Medicine Göttingen
• 2006: Intern in Neurology, Dept. of Neurology, University of Freiburg, Germany
• 2006: Intern in Internal Medicine, University of Toronto, Canada
• 2005: Intern in Surgery, Nanjing Medical University, China

• Mechanisms of acute axonal degeneration in the optic nerve in vivo.
  Knöferle J, Koch JC, Ostendorf T, Michel U, Planchamp V, Vutova P, Tönges L, Stadelmann C, Brück W, Bähr M, Lingor P.
  Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6064-9. doi: 10.1073/pnas.0909794107. Epub 2010 Mar 15.
  [PubMed]
• Imaging of rat optic nerve axons in vivo.
  Koch JC, Knöferle J, Tönges L, Michel U, Bähr M, Lingor P.
  Nat Protoc. 2011 Nov 3;6(12):1887-96. doi: 10.1038/nprot.2011.403.
  [PubMed]
• ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.
  Koch JC, Tönges L, Barski E, Michel U, Bähr M, Lingor P.
  Cell Death Dis. 2014 May 15;5:e1225. doi: 10.1038/cddis.2014.191.
  [PubMed]
• Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration.
  Zhang JN, Michel U, Lenz C, Friedel CC, Köster S, d’Hedouville Z, Tönges L, Urlaub H, Bähr M, Lingor P, Koch JC.
  Sci Rep. 2016 Nov 15;6:37050. doi: 10.1038/srep37050.
  [PubMed]
• Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonaldegeneration in CNS neurons.
  Koch JC, Bitow F, Haack J, d’Hedouville Z, Zhang JN, Tönges L, Michel U, Oliveira LM, Jovin TM, Liman J, Tatenhorst L, Bähr M, Lingor P.
  Cell Death Dis. 2015 Jul 9;6:e1811. doi: 10.1038/cddis.2015.169.
  [PubMed]
• ROCK inhibition in models of neurodegeneration and its potential for clinical translation.
  Koch JC, Tatenhorst L, Roser AE, Saal KA, Tönges L, Lingor P.
  Pharmacol Ther. 2018 Sep;189:1-21. doi: 10.1016/j.pharmthera.2018.03.008. Epub 2018 Apr 3. Review.
  [PubMed]
• See more ->

• 2014: Award for the best publication of the year 2014 at the Dept. of Neurology, University Medicine Göttingen, Germany
• 2011: Award for the best young academics publication at the University of Göttingen in the year 2010
• 2009 – 2011: Research Grant from the German Science Foundation (DFG)
• 2002 – 2003: China Scholarship Program by the Alfried Krupp von Halbach Foundation
• 2001 – 2006: Scholarship of the German Academic Scholarship Foundation (Studienstiftung des deutschen Volkes)

• 2016: Habilitation” for Neurology (“Privatdozent”; German University lecturer) at University Medicine Göttingen, Germany
• 2013 – present: Seminar “Neurology” for advanced medical students at University Medicine Göttingen
• 2010 – present: Co-Supervision of 6 MD theses, 1 PhD thesis, 1 master thesis
• 2008 – present: Courses, lectures and tutorials for the Göttingen Graduate School for Neurosciences, Biophysics and Molecular Biosciences (GGNB)
• 2010, 2014: Lecture “Functional Neuroanatomy” for graduate students of Molecular Medicine at the University of Göttingen
• 2009 – 2013: Course “Bedside Neurology” for advanced medical students at University Medicine Göttingen
• 2012: Implementation of a new organization and innovative curriculum for the course “Bedside Neurology” at University Medicine Göttingen
• 2009: Organization of the first “German-Chinese Summer School in Neurology” in Göttingen
• 2007 – 2011: Course “Neurology for Physiotherapists” for students of the School for Physiotherapy, University Medicine Göttingen
• 2006 – 2009: Course “Neurological Examination Skills” for medical students at University Medicine Göttingen

Basic neuroscience:

• Main research focus: Mechanisms of axonal degeneration in neurodegenerative diseases
• Techniques: animal models, animal surgery, stereotactic surgery, in-vivo live-imaging, production and application of adeno-associated viral vectors, primary neuronal cell culture, microfluidic chambers, electron-, epifluorescence-, confocal- and 2-photon-microscopy, immunoblotting, immunohistochemistry, PCR

Clinical neurology:

• Main focus: Neurodegenerative diseases: Motoneuron diseases and movement disorders
• 2015 – present: Director of the outpatient department for Motoneuron diseases
• 2012 – present: Director of the outpatient department for Botulinumtoxin therapy
• 2014 board certification for “Clinical botulinumtoxin therapy” (AG Botox)
• 2012 – present: Vice-Director of the outpatient department for movement disorders & Parkinson
• 2007 – present: Consultant in the outpatient department for Parkinson’s disease
• 2014: Certificate “EEG” of the German Federation of Clinical Neurophysiology (DGKN)
• 2014: Board certificate “Clinical cerebrospinal fluid diagnostics” (DGLN)
• 2017: Board certificate “Neurological intensive care medicine” (Ärztekammer)

• Kongress der Deutschen Gesellschaft für Neurologie (DGN), Düsseldorf, Germany, 2015
  Koch JC, Bitow F, Haack J, Cerdeira M, Bähr M, Lingor P. Effekte von Alpha-Synuclein auf Neuritenmorphologie, axonalen Transport und Autophagie.
• Annual meeting of the Society for Neuroscience (SfN), Chicago, USA, 2015
  Tatenhorst L, Walle H, Eckermann K, Dambeck V, Fonseca L, Lopes da Fonseca T, Koch JC, Tönges L, Bähr M, Outeiro TF, Zweckstetter M, Lingor P. The ROCK inhibitor Fasudil alters alpha-synuclein aggregation in vitro and improves motor and cognitive behavior in alpha-synuclein.A53T.tg mice in vivo.
• Federation of European Neuroscience Societies (FENS) Summer School “Shared mechanisms and specificity in neurodegenerative diseases”, Bertinoro, Italy, 2015
  Koch JC, Cerdeira M, Lingor P. Alpha-Synuclein affects neurite morphology and axonal degeneration in CNS neurons via modulations of autophagy, vesicle transport and axonal energy supply.
• Federation of European Neuroscience Societies (FENS) Meeting, Milano, Italy, 2014.
  Koch JC, Haack J, Bitow F, Michel U, Bähr M,  Lingor P. Effects of alpha-synuclein overexpression on neurite integrity in vitro and in vivo.
• FENS-Meeting, Barcelona, Spain, 2012.
  Koch JC, Solis GP, Bodrikov V, Michel U, Haralampieva D, Shypitsyna A, Tönges L, Bähr M, Lingor P, Stuermer CAO. Overexpression of reggie-1/flotillin-2 in mammalian CNS neurons promotes axon growth and regeneration in vitro and in vivo.
• ADPD-Meeting, Barcelona, Spain, 2011
  Bitow F, Haack J, Koch JC, Barski L, Kügler S, Bähr M, Lingor P. Effects of disease-relevant alpha-synuclein- and LRRK2- mutants on neurital dynamics in primary midbrain dopaminergic neurons.
• FENS-Meeting, Amsterdam, Netherlands, 2010.
  Koch JC, Knöferle J, Ostendorf T, Tönges L, Michel U, Stadelmann C, Bähr M, Lingor P. Mechanisms of axonal degeneration in the central nervous system – the link between calcium and autophagy.
• Society for Neuroscience (SFN) Meeting, Chicago, USA, 2009.
  Koch JC, Michel U, Tönges L, Knöferle J, Bähr M,  Lingor P. AAV-mediated specific knock-down of RhoA, ROCK2 and LIMK1 promotes axonal regeneration in retinal ganglion cells and midbrain dopaminergic neurons.
• German Neuroscience Society Meeting, Göttingen, Germany, 2009.
  Koch JC, Michel U, Knöferle J, Tönges L, Bähr M, Lingor P. Specific knock-down of RhoA, ROCK2 and LIMK1 promotes neurite outgrowth and axonal regeneration.
• FENS-Meeting, Geneva, Switzerland, 2008.
  Koch JC, Knöferle J, Stadelmann C, Bähr M, Lingor P. Ultrastructural analysis of acute axonal degeneration following optic nerve crush in rats.

• ROCK inhibition in models of neurodegeneration and its potential for clinical translation.
  Koch JC, Tatenhorst L, Roser AE, Saal KA, Tönges L, Lingor P.
  Pharmacol Ther. 2018 Sep;189:1-21. doi: 10.1016/j.pharmthera.2018.03.008. Epub 2018 Apr 3. Review.
  [PubMed]
• Alpha-synuclein and iron: two keys unlocking Parkinson’s disease.
  Lingor P, Carboni E, Koch JC.
  J Neural Transm (Vienna). 2017 Aug;124(8):973-981. doi: 10.1007/s00702-017-1695-x. Epub 2017 Feb 6. Review.
  [PubMed]
• The role of autophagy in axonal degeneration of the optic nerve.
  Koch JC, Lingor P.
  Exp Eye Res. 2016 Mar;144:81-9. doi: 10.1016/j.exer.2015.08.016. Epub 2015 Aug 24. Review.
  [PubMed]
• Axonal degeneration as a therapeutic target in the CNS.
  Lingor P, Koch JC, Tönges L, Bähr M.
  Cell Tissue Res. 2012 Jul;349(1):289-311. doi: 10.1007/s00441-012-1362-3. Epub 2012 Mar 6. Review.
  [PubMed]

• Autophagy in the degeneration of optic nerve and spinal cord axons. Book chapter in: AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging.
  Koch JC, Ribas VT, Lingor P
  Volume 8 and 9, 2016.
• Targeting Neurological Disease with siRNA. Controlled Genetic Manipulations.
  Koch JC, Bähr M, Lingor P.
  2012. pp 97-111.

• BMC Neurology (Associate Editor)
• Journal of Neuroscience
• European Journal of Neuroscience
• Neuroscience
• Experimental Neurology
• Brain Pathology
• Autophagy
• Journal of Neurochemistry
• European Journal of Clinical Investigation
• Cellular Physiology and Biochemistry
• International Journal of Molecular Sciences
• Deutsche Forschungsgemeinschaft (DFG)

• German Neuroscience Society (NWG/FENS)
• International Federation of Clinical Neurophysiology, German section (DGKN)
• German Society for Cerebrospinal Fluid Diagnostics and Clinical Neurochemistry (DGLN)
• German Parkinson Association (DPG)
• International Neurotoxin Association (INA)